Endocrine Abstracts

A young fit male readmitted with three weeks history of malaise, pale stool, dark urine, pruritus with recent travel to Greece. He denied alcohol, illicit drug abuse. Examination revealed jaundice.Investigation showed cholestatic liver impairment with Bilirubin: 448 μmol/l (7-35), ALT: 134 IU/l (17–63), ALP: 190 IU/l (32–91), HDL 0.34 mmol/l (>0.9). Viral Screen, autoantibody, porphyria and tumour markers were negative. CT Abdomen show...

Background and aims: Diabetes insipidus (DI) is a common complication after transsphenoidal surgery (TSS), but resolves in the majority of patients. We determined the osmolalities and timing of DI most that best predicted long-term outcome.Methods: Case series study randomly including 54 patients out of total 99 patients who underwent transsphenoidal surgery over 18 months. Follow up information was ascertained from clinic review or by telephone intervie...